Case Studies

Translational Research Facility – Location S

Project Specifications:

Fosdick & Hilmer provided overall project management and engineering services for design of mechanical, electrical, plumbing, fire protection and automation systems related to this 400,000 GSF, 12-story, $140 million medical research facility.

Each research floor is based on an integrated model of wet lab and dry lab research space with focus on interaction of researchers from different disciplines. Typical laboratory floors were laid out to optimize the relationship between lab, lab support and offices so people are encouraged to interact.

Open layouts facilitate “Matrix Research” where different research divisions can be co-located to work on inter-related thematic work. A central circulation spine links to the existing research tower (Location R) and provides interaction opportunities such as meeting rooms, informal break-out space and quieter spaces of respite. All these spaces are accessible on a wireless network allowing research work to break out of the lab.

Double volume overlooks and vistas through glass curtain wall bring a sense of connection to the exterior as well as bringing in light.

Major program requirements included the following:

  • 15,000 SF Tier III (Tier IV Fault Tolerant) data center including a super computer that supports genomic research by storing, organizing, indexing and analyzing enormous amounts of patient and research data.
  • Data center serves the Computational Medicine Center; the Integrating Clinical Information System (ICIS) which provides links to systems and databases; an enterprise-wide comprehensive clinical and financial information system; web portals for cystic fibrosis, juvenile rheumatoid arthritis, diabetes and liver transplant treatment which allow patients and families to view lab results, track patient progress and communicate with caregivers.
  • Wireless access at all locations in the building to enable improvements in education, quality and the overall patient care experience



  • Facility construction meets CDC/NIH requirements for Biological Safety Level 1 and 2.
  • Vector Production Facility for manufacturing viral vectors and other products for Phase I & II clinical trials, is designed for compliance with cGMP regulations (21 CFR Parts 210 & 211) with Biosafety Level 2 (BL-2) cleanrooms.
  • Sustainable design features were added when allowed within the project budget.
    • Natural light and views were prioritized on all floors
    • Occupancy sensors are installed in every space to control the lighting, HVAC supply air flow, and lab hood exhaust air flow.
    • Propylene glycol water loop recovers sensible energy from the exhaust air and transfer it to the supply air.