Case Studies

Animal Room Expansion

Project Specifications:

Fosdick & Hilmer provided overall project management and engineering services for design of mechanical, electrical, plumbing, fire protection, IT and automation systems related to this 520,000 GSF, 9-story, medical research facility.

Flexibility was a key driver in the new research facility at Cincinnati Children’s, which includes both wet and dry laboratory space. Upper floors, where the dry labs are located, were designed for cost effective modification of the essential M/E/P/FP and automation systems in the future for conversion into vivarium space. The building layout also allows for one final addition to the south, while the lab space was designed to be modular in order to meet future needs.

Research programs housed in the tower include:

  • Molecular Immunology
  • Developmental Biology
  • Molecular Cardiovascular Biology
  • Pulmonary Biology
  • Infectious Diseases
  • Nephrology
  • Human Genetics
  • General and Community Pediatrics
  • Biostatistics
  • Nursing Research
  • Clinical Investigation Program
  • Clinical Trials Office
  • Health Policy and Clinical Effectiveness
  • Emergency Medicine
  • Imaging Research Center
  • Clinical Epidemiology
  • Endocrinology
  • Pediatric Informatics



  • Renovation of an occupied building.
  • All animal facilities comply with AAALAC guidelines. [all animal facilities have received AAALAC accreditation]
  • All animal facilities comply with guidance, policies and regulations established by NIH’s Office of Laboratory Animal Welfare, including NIH Grants Policy Statement.
    • All animal facilities comply with ILAR’s Guide for the Care and Use of Laboratory Animals.
    • All animal facilities comply with PHS’s Policy on Humane Care and Use of Laboratory Animals.
  • Vivarium construction meets biosafety practice and policy established in CDC/NIH’s publication Biosafety in Microbiological and Biomedical Laboratories.
  • Vivarium construction meets CDC/NIH requirements for Animal Biological Safety Level 1 and 2 (ABSL-1 & ABSL-2).
  • Individually ventilated cages using modular animal cage systems (MACS).
  • Laboratory drug processing areas comply with cGMP (21 CFR 58) Good Laboratory Practice for Nonclinical Laboratory Studies and with cGMP (21 CFR 312) Guidance for Industry for Phase 1 Investigational Drugs.
  • Digital control systems to precisely maintain air pressurization differences between spaces and the independent temperature requirements of each laboratory and office.
  • IT systems allowing quick access and retrieval of critical information for effective colony and facility management.
  • Wireless access at all locations in the building to enable improvements in education, quality and the overall patient care experience.
  • Energy efficient cage wash facilities.
  • Construction phase planning was provided to facilitate the existing building’s operations, as well as those of the surrounding buildings, throughout the construction period.
  • Sustainable design features were added when allowed within the project budget.
    • Natural light was prioritized on all floors
    • Occupancy sensors are installed in every space to control the lighting, HVAC supply air flow, and lab hood exhaust air flow.
    • Propylene glycol water loop recovers sensible energy from the exhaust air and transfer it to the supply air.